Co-amorphization of olanzapine for solubility enhancement
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چکیده
منابع مشابه
Development of Microemulsion for Solubility Enhancement of Clopidogrel
Clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. The aim of this investigation was ...
متن کاملDevelopment of Microemulsion for Solubility Enhancement of Clopidogrel
Clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. The aim of this investigation was ...
متن کاملdevelopment of microemulsion for solubility enhancement of clopidogrel
clopidogrel, an inhibitor of platelet aggregation, selectively inhibits the binding of adenosine diphosphate (adp) to its platelet receptor and the subsequent adp-mediated activation of the glycoprotein gpiib/iiia complex, thereby inhibiting platelet aggregation. oral bioavailability of clopidogrel is very low (less than 50%), due to its poor water solubility. the aim of this investigation was ...
متن کاملSolubility enhancement in supercritical solvents
The enhancement of solubility of a solid in a supercritical solvent is interpreted with emphasis placed on binary mixtures of the second class. The selection of supercritical solvent ; the choice of temperature and pressure for supercritical fluid extractions; the characteristics of solubility curves between and in the vicinities of the upper critical and the lower critical end points; the effe...
متن کاملAdvances in Solubility Enhancement Techniques
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. The major problem encountered with formulation development of new chemical entities as well as for the generic development is low aqueous solubility. It ...
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ژورنال
عنوان ژورنال: Annals of Medicine
سال: 2019
ISSN: 0785-3890,1365-2060
DOI: 10.1080/07853890.2018.1561801